This was a multi-centre randomised blinded controlled trial. The main aim being to test a method which may increase the number of live births from treatment and reduce miscarriage rates by using a different method of selecting ‘good’ sperm. 

A secondary part of this trial was to find out more about what makes ‘good’ sperm different from the others. One possible difference may be how the DNA is packaged in the sperm cell or in the amount of damage that the sperm DNA caries. If it is the latter, then changes in lifestyle could potentially improve the couple’s chance of having a baby.

The trial findings were published in February 2019 in the medical journal The Lancet. 

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