Centre for Human Reproductive Science

FUTURE GENERATIONS

DIAGNOSIS

In the natural conception process millions of sperm are selected down to tens or hundreds reaching the egg, how this occurs and what may allow the best sperm to be selected or others to be removed are also key questions for assisted conception treatment.

IMPROVEMENT

Data from many labs around the world suggests that certain factors in diet may affect sperm quality. Our team are particularly interested not just in whether we can improve male fertility, but whether changes have improved health implications for the children born afterwards

TREATMENT

HABSelect was a multicentre randomised blinded controlled trial, designed to test a sperm selection method which may increase the number of live births and reduce miscarriage rates

WHAT WE DO

The Centre for Human Reproductive Science (ChRS) is a Human Fertilisation and Embryology Authority (HFEA) licenced research centre, established in December 2006 to further develop research and innovation in fertility diagnosis and treatment.

The ChRS team have made advances in various areas, these include achievements in:

  • Translational medicine, such as the invention of the male Fertell over-the-counter home fertility test.
  • The first detailed studies of ion channels in human sperm.
  • Detailed characterisation of the events occurring in sperm in response to steroid hormones, including the discovery of slow calcium oscillations, now thought to possibly regulate to how sperm swim. To date the identity of the cell receptors involved has not been clearly understood.
  • Substantial follow-up data of children born through IVF treatment to check for increased risks associated with the treatment.
  • ChRS also has psychology collaborations to actively pursue research enabling better understanding of patient feelings and care during fertility treatment; and issues surrounding motivation to be a donor and receipt of donor gametes.

The ChRS does not directly enter into patient treatment or diagnosis being focussed upon research.

SEARCH FOR WORDS USING OUR… REPROPEDIA DICTONARY

GET TO KNOW US AND WHAT WE DO… MEET THE TEAM

OUR RESEARCH

Being a Healthcare Scientist and Researcher – Jackson’s Story

Dr Jackson Kirkman-Brown explains how the Health Education England/National Institute for Health Research Senior Clinical Lectureship has allowed him to stay clinically active whilst having the opportunity to lead on research that has a significant impact on those...

The role of sperm DNA in early miscarriage

Applications are invited for a 3-year fully-funded PhD Studentship for UK or EU Nationals starting as soon as possible in the Tommy’s National Centre for Miscarriage Research. Applications must be made before Thursday, June 23, 2016. The successful PhD project...

Now you can know the real details of sperm motility! Our new flagellum tracking software FAST is now live and is free to download and use! Find out more at: https://t.co/0tS5Ie3ce0 #whywedoscience @BWC_NHS @IMSR_UoB #rapidsperm

So important for proper genetic counselling prior to NIPT so stories like this don’t become the norm.

As an aside, I despair that the journalist criticising the transfer of facts resorted to the colloquialism ‘there are short genes in the family’ 🤨 https://t.co/NYdOnBMCbN

#OnThisDay day in 1944, John Rock and Miriam F. Menkin fertilized the first human egg in a test tube, proving that in vitro fertilization was possible in humans. It would still be 34 years until the first IVF baby was born in 1978! #IVF #physiology

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THANKS FOR THE SUPORT